Mechanisms of autophagic regulation of Aβ metabolism against Alzheimer’s disease

Project: Research project

Project Details


Autophagy, the pathway a brain cell uses to dispose damaged structures inside the cell, is impaired in Alzheimer’s disease (AD). Brain cells produce amyloid, a toxic peptide that causes AD. Our research will show how activated autophagy can recognize and clears amyloids in different types of brain cells, and how to increase the activity of this pathway to accelerate the disposal of amyloids.
Effective start/end date7/1/182/28/22


  • BrightFocus Foundation (A2018100S)


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.