Modulation of Dravet Syndrome by Nedd4-2

Project: Research project

Description

GOAL: To determine if abolishing the Nedd4-2 recognition site in mice using the Scn1aY1986A allele rescues Scn1a+/- Dravet syndrome phenotypes by increasing steady-state Nav1.1 levels.
StatusFinished
Effective start/end date4/12/164/12/17

Funding

  • Xenon Pharmaceuticals Inc. (Agmt 4/12/16)

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Myoclonic Epilepsy
Alleles
Phenotype