Parkinson’s disease (PD) is the second most common age-related, progressive neurodegenerative disorder without effective treatment. Through our efforts over 20 years, we have established a new genetic locus on chromosome 20 and identified a new PD-causative gene. This project is designed to understand the molecular mechanism by which mutations in this new PD gene cause PD. Understanding the molecular mechanism may provide a pathophysiological basis for design of rational therapies for PD.
|Effective start/end date||9/30/16 → 7/31/21|
- National Institute of Neurological Disorders and Stroke (5R01NS099623-05)