Mouse model studies of TMEM230-linked Parkinson's disease

Project: Research project

Project Details

Description

Parkinson’s disease (PD) is the second most common age-related, progressive neurodegenerative disorder without effective treatment. Through our efforts over 20 years, we have established a new genetic locus on chromosome 20 and identified a new PD-causative gene. This project is designed to understand the molecular mechanism by which mutations in this new PD gene cause PD. Understanding the molecular mechanism may provide a pathophysiological basis for design of rational therapies for PD.
StatusActive
Effective start/end date9/30/167/31/21

Funding

  • National Institute of Neurological Disorders and Stroke (5R01NS099623-05)

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