Multiplatform Variant Prediction (MVP) in Epilepsy

Project: Research project

Project Details


The goal of this Center without walls is to improve our understanding of the consequences of variants in non-ion channel genes on protein function in patients with epilepsy. These studies will provide a platform for experimental and computational classification of variants of uncertain significance (VUS) that are currently a significant complication in clinical genetic testing. Moreover, we will investigate pathogenic mechanisms implicated in epilepsy beyond the ion-channels; these steps are crucial in the pursuit of novel therapeutic development and the promise of personalized medicine.
Effective start/end date9/15/207/31/25


  • University of Michigan (SUBK00011889AMD2//5U54 NS117170-03)
  • National Institute of Neurological Disorders and Stroke (SUBK00011889AMD2//5U54 NS117170-03)


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