Neuromodulation and Neurorehabilitation for Treatment of Functional Deficits after mTBI + PTSD

Project: Research project

Project Details


The purpose of this study is to determine the magnitude of immediate and sustained effects of a current clinical standard of the interactive computer attention processing training (APT)1 combined with intermittent theta burst stimulation (iTBS) and to determine how APT + iTBS changes the neurocognitive system of atten-tion in Veterans, Active Duty Military Personnel and Civilians with persisting attention deficits related to Mild Traumatic Brain Injury (mTBI) and/or Post Traumatic Stress Disorder (PTSD). This study is a randomized clinical trial (RCT) that directly addresses the intent of the Neurosensory and Rehabilitation Research Award program announcement (W81XWH-14-CRMRP-NSRRA), specifically the Clinical Trial Research Focus Area of Neuromusculoskeletal Rehabilitation. The proposed work will impact the health care needs of Active Duty Military Personnel and Veterans with mTBI and PTSD (mTBI + PTSD) because anticipated findings will ad-vance knowledge of long-term remediation of attentional deficits and how this translates to improved functional task performance in daily life within their communities. This research is also likely to provide new avenues for treatment research for all TBI, fundamentally advancing the field of TBI neurorehabilitation.
Effective start/end date9/30/159/29/20


  • Chicago Association for Research and Education in Science (Pape-0020 // W81XWH-15-1-0516)
  • U.S. Army Medical Research and Materiel Command (Pape-0020 // W81XWH-15-1-0516)


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