Parkinson's Progressive Markers Initiative (Steering Committee 2013)

Parkinson’s Progression Markers Initiative (PPMI) is an observational clinical study to comprehensively evaluate a cohort of recently diagnosed Parkinson's Disease patients and healthy subjects using advanced imaging, biologic sampling and clinical and behavioral assessments to identify biomarkers of Parkinson’s disease progression. PPMI will be carried out over five years at 24 clinical sites in the United States, Europe, and Australia, and requires the participation of 400 Parkinson’s patients and 200 control participants. Data and samples acquired from study participants will enable the development of a comprehensive Parkinson’s database and biorepository, which will be available to the scientific community to conduct field-changing research. PPMI is made possible by the concerted efforts of a number of collaborators. This study is sponsored by The Michael J. Fox Foundation for Parkinson’s Research.