Pathways linking Early Adversity and Support to Behavioral and Physical Health

Project: Research project

Project Details

Description

Drs. Chen and Miller co-direct the Foundations of Health Research Center and will contribute jointly to this project, including: (a) advise on the collection, processing, and shipment of blood samples; (b) oversee the conduction of peripheral blood assays at all time points. These assays will be conducted in their research center; (c) supervise quality control checks on these data; (d) provide guidance about interpretations related to stress-immunology data; and (e) participate in statistical analyses and manuscript preparation.

To index low-grade inflammation, we will measure serum concentrations of C-reactive protein (CRP) and the cytokines interleukins-6, 8, 10, and tumor necrosis factor-alpha. All of these molecules are widely utilized biomarkers of inflammation. These assays will all be conducted at Northwestern University under the direction of Drs. Chen and Miller. Metabolic outcomes will be assayed by NorthShore University Health Systems-Evanston Hospital, with Dr. Chen as the point person.
StatusActive
Effective start/end date6/20/185/31/23

Funding

  • University of Notre Dame (203344NU // 1R01HD091235-03)
  • National Institute of Child Health and Human Development (203344NU // 1R01HD091235-03)

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