Postpartum Perineal Pain after Obstetric Anal Sphincter Injuries: A Randomized Clinical Trial

Project: Research project

Project Details


Obstetric anal sphincter injuries (OASIS) encompass both third and fourth degree perineal
tears. These tears can have a significant impact on women's quality of life in the short and long
term. The immediate complication of this severe perineal injury is unrelenting perineal pain.
Women can also experience postpartum depression, dyspareunia, and altered sexual function
after OASIS.

This is a randomized controlled trial to study the effects of three interventions (placebo, low
dose intravenous ketamine plus epidural morphine, or epidural morphine alone) on acute pain
after OASIS.
Effective start/end date9/1/188/31/21


  • Northwestern Memorial Hospital (NMH Agmt #15 Exhibit B.6)


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