Pre-clinical & clinical studies of breast cancer prevention with transdermal anti-progesterone agent

Project: Research project

Project Details

Description

In the coming year, we will complete our pre-surgical window trial (NU-12B09, 2-10 weeks of telapristone 12.5 mg in Stage I-II breast cancer patients); initiate an NCI-funded comparison of oral and transdermal telapristone (CDB4124) in a window setting; and continue preclinical evaluation of CDB-4124 in comparison to classical and additional novel anti-progestins. However, the major focus of the experiments described below will be to generate data to support a Phase II prevention trial using telapristone in BRCA mutation carriers.
StatusFinished
Effective start/end date10/1/149/30/16

Funding

  • Breast Cancer Research Foundation (Form 08/22/2014)

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