Prehospital Airway Control in Trauma (PACT) Trial

: Study Design/Setting: We propose the Prehospital Airway Control in Trauma (PACT) trial, a 5 year (4-year enrollment) open label, multi-center, stepped wedge cluster randomized trial comparing the effect of a standard strategy of airway management vs a strategy of first attempt with supraglottic airway (SGA) for prehospital trauma patients. Study Aims: LITES Task Order 005 aims to compare different methods of trauma airway management in the prehospital setting with the following aims: • AIM#1: To compare the effect of a standard strategy of airway management vs. a strategy of first attempt with supraglottic airway (SGA) on 24-hour survival after traumatic injury. • AIM#2: To compare the effect of a standard strategy of airway management vs. a strategy of first attempt with supraglottic airway (SGA) on hospital survival after traumatic injury. • AIM#3: To compare the effect of a standard strategy of airway management vs. a strategy of first attempt with supraglottic airway (SGA) on major adverse events after traumatic injury.