Cariprazine is a novel antipsychotic drug with a favorable side effect profile. Understanding the pharmacology of its actions on cognition and psychosis is important to differentiate it from other antipsychotic drugs. This revised proposal is focused on the role of the effects of cariprazine on the dopamine D3 receptor to enhance cognitive function and its antipsychotic action, using microdialysis in the ventral hippocampus and ventral striatum (nucleus accumbens).
|Effective start/end date||4/15/17 → 4/15/18|
- Allergan Sales, LLC (Prot #BIO-17-1142)