PDGF-BB (Platelet Derived Growth Factor-B chain homodimer) is a polypeptide growth factor released from platelets and acts early in the wound healing cascade as a chemoattractant and mitogenic agent, for both osteoprogenitor cells and differentiated osteoblasts [1-3]. PDGF-BB also plays an important role in the formation of new blood vessels[2, 4]. These properties make PDGF-BB’s role vital in the recruitment and amplification of the osteoblast lineage cells and promoting healing at the bone fusion site [5-7].
|Effective start/end date||5/9/18 → 5/9/21|
- Wright Medical Technology, Inc. (Agmt 05/09/18)
Proto-Oncogene Proteins c-sis
Intercellular Signaling Peptides and Proteins
Bone and Bones
platelet-derived growth factor BB