REDD1 dissociates the therapeutic and adverse effects of glucocorticoids in skin

Project: Research project

Project Details

Description

Glucocorticoids remain the most commonly used anti-inflammatory drugs in dermatology, however, their use is limited by the development of side effects, particularly skin atrophy. We discovered that REDD1 is causatively involved in skin atrophy. The proposed studies will test the novel concept of safe anti-inflammatory therapy in which glucocorticoids are combined with REDD1 inhibitors.
StatusActive
Effective start/end date3/22/172/28/22

Funding

  • National Institute of Allergy and Infectious Diseases (5R01AI125366-05)

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