Our study aims to compare accuracy of a combined EEG/MEG source localization model with intracranial EEG interictal and ictal recordings from epilepsy surgery patients. This will allow us to compare the relative contributions of scalp EEG and MEG recordings to the dipole model. In selected patients with comprehensive lobar coverage, we will be able to use the EEG data to map an invasive voltage field which can be compared to the presurgical surface ESI and MSI models. We will correlate the various source models and determine if the co-localization of the electrical or magnetic source within the surgical cavity affects outcome. In a second step, we would analyze the added value of FDG-PET and subtraction SPECT in comparison to ESI and MSI to impact surgical decision, invasive implantation and outcome. We would also co-register the various diagnostic datasets to determine the concordance with surgical resection and impact on outcome.
|Effective start/end date||7/1/14 → 6/30/16|
- American Brain Foundation (ABF32014)