The ability of SRs to recognize a wide variety of pathogens suggests additional roles in host defense and relationships with toll-like receptors (TLRs), which instruct innate immunity. Because virtually nothing is understood about SRs in human skin and their functions in innate immune responses, this proposal aim to evaluate SR expression and their physical and biological interactions with TLRs in 2D and 3D cutaneous models.
|Effective start/end date||7/1/18 → 6/30/19|
- Dermatology Foundation (AGREEMENT 3/22/18)
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