This proposal will determine whether gene expression profiling of individual cells in a noninvasive sample of nasal tissue from a patient with IPF is feasible. This proposal will also determine whether single-cell transcriptomic analysis can be used to identify new cell types present in the nasal airways of patients with IPF. This research may form a foundation for the development of marker tests for diagnosis, prognosis, and prediction of response to therapy in IPF, and may uncover new targets for therapy.
|Effective start/end date||7/1/20 → 6/30/21|
- Respiratory Health Association of Metropolitan Chicago (RHA2020-01-IPF)