The goal of the SAPS Smoking Cohort Study is to evaluate asthma outcomes in asthmatics who smoke in preparation for launch of a clinical trial, the Theophylline or Montelukast as Add-On Therapy in Smokers with Asthma Not Controlled with Combination ICS/LABA (TOM Trial). This proposed full-scale, randomized, clinical trial will evaluate the comparative effectiveness of three competing approaches to add-on therapy in smoking asthmatics with mild to moderate persistent asthma who are not adequately controlled by the currently recommended asthma treatments, i.e., a combination of low-dose inhaled corticosteroids and long-acting beta-agonist, in terms of symptomatic and physiologic endpoints of asthma management.
|Effective start/end date||2/1/13 → 1/31/16|
- American Lung Association (Award Letter 11/29/12//5R34HL109482)
- National Heart, Lung, and Blood Institute (Award Letter 11/29/12//5R34HL109482)