We propose to study the structure and mechanism of proteins, nucleic acids, and their complexes. The central theme of the work is the understanding of the atomic mechanism of crucial biological macromolecules through a combination of structural and biophysical studies. The goal of the research is to reveal paradigms for understanding fundamental biological processes common to all organisms, including humans.
|Effective start/end date||9/30/17 → 8/31/22|
- National Institute of General Medical Sciences (5R35GM118108-04)