Project Details
Description
Aim 1: Define the GU microbiome across the life course of healthy women
a) Assess the stability or instability of the GU microbiome over time.
b) Identify if there is a dominant GU microbiome during different life phases.
c) Investigate whether instability in GU microbiome is associated with changes in self-perceived bladder health or the development of lower urinary tract symptoms.
Aim 2: Develop a database of commonly occurring elements of contamination associated with the GU microbiome (acquired through vaginal sampling), which will be used to build a statistical model of potential contamination that can be applied to future microbiota analysis on voided urine samples.
a) Assess the stability or instability of the GU microbiome over time.
b) Identify if there is a dominant GU microbiome during different life phases.
c) Investigate whether instability in GU microbiome is associated with changes in self-perceived bladder health or the development of lower urinary tract symptoms.
Aim 2: Develop a database of commonly occurring elements of contamination associated with the GU microbiome (acquired through vaginal sampling), which will be used to build a statistical model of potential contamination that can be applied to future microbiota analysis on voided urine samples.
| Status | Finished |
|---|---|
| Effective start/end date | 7/1/17 → 12/31/19 |
Funding
- American Urogynecologic Society (Agmt 9/4/18//U01DK106786)
- National Institute of Diabetes and Digestive and Kidney Diseases (Agmt 9/4/18//U01DK106786)
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