The 4D nucleome of muscle regeneration in ischemia-induced tissue damage and repair

Project: Research project

Project Details

Description

In this U01 proposal with Dr. Yarui Diao from Duke University, we will process all the genomic data, including Hi-C, ChIP-Seq, and RNA-Seq experiments. We will identify differential gene expression for the normal and disease cells, predict ChIP-Seq peaks, and also perform motif analysis. For the Hi-C data, we will systematically identify chromatin loops, TADs, compartments, as well as dynamic 3D genome features.
StatusActive
Effective start/end date9/20/208/31/21

Funding

  • Duke University (A034155-01//1U01-HL156064-01)
  • National Heart, Lung, and Blood Institute (A034155-01//1U01-HL156064-01)

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