The Impact of Tube Length and Flow Rate on Oxygen Fraction of Inspired Oxygen Delivered Versus Received Using High Flow Nasal Cannula

Project: Research project

Project Details

Description

The onset of COVID-19 ignited innovative clinical reasoning and raised questions in the area of oxygen delivery to patients with acute hypoxic respiratory failure. While the benefits of using High Flow Nasal Cannula (HFNC) were evidenced in the literature for patients with COVID19, the application sometimes required unconventional methods due to the strains on the medical system during the pandemic. Clinicians need a resource to accurately adapt settings for FiO2 and flow if there is a clinical need to adjust the length of HFNC delivery tubing. This study is designed with two arms: first to measure the impact of changes in HFNC tubing length on the fraction of inspired oxygen (FiO2) received compared to what was delivered; then second, to measure the impact of flow rate on fraction of inspired oxygen received at various tube lengths. We hypothesize that the length of tubing used for oxygen delivery using a high flow nasal cannula device will impact the fraction of inspired oxygen delivered versus the fraction of inspired oxygen received by the patient at various flow rates. AIM 1: Establish the relationship between the fraction of inspired oxygen delivered compared to the dose received at clinically relevant HFNC tubing lengths. Compared to standard tubing lengths, we hypothesize that increases in tubing length will decrease the fraction of inspired oxygen received compared to the dose delivered. AIM 2: Establish the relationship of flow rate on fraction of inspired oxygen received at clinically relevant tubing lengths. We hypothesize that the impact of tubing lengths on fraction of inspired oxygen received can be mitigated by adjusting flow rate in relation to tubing length.
StatusFinished
Effective start/end date4/1/224/1/23

Funding

  • American Physical Therapy Association (Ryan AGMT 4/13/22)

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