This proposal addresses several PCRP focus areas including genetics, therapy, and biomarker development. The proposed studies will dissect the mechanisms and consequences of lncRNA PRCAT71 expression in PCa. Moreover, the bioinformatics portion of this proposal will determine the potential use of PRCAT71 as the prognostic markers for PCa. Finally, this proposal will identify new therapeutic strategy targeting AR-PRCAT71 feedback loop to treat patients with CRPC.
|Effective start/end date||9/1/21 → 8/31/23|
- U.S. Army Medical Research and Materiel Command (W81XWH2110146)
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