We hypothesize that CD44+ CSCs maintain CD81 levels to promote exosome production, immune suppression, and CSC properties (stemness). We aim to examine the effects of modulated CD44 and CD81 on cancer exosome-mediated cross talks with immune cells, and to determine the intrinsic role of CD81 in CSC stemness and metastasis.
|Effective start/end date||9/1/18 → 8/31/20|
- Northwestern Memorial Hospital (AGMT 12/3/18)
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