TOP2A effects on transcription in gliomas: implications for personalized therapy

Project: Research project

Description

This proposal aims to study the role of Topoisomerase IIA (TOP2A) in transcriptional regulations in glioblastomas, and explore therapeutic targeting using intratumoral etoposide for this lethal form of brain cancer.
StatusActive
Effective start/end date9/1/178/31/20

Funding

  • Office of the Director, National Institutes of Health (7DP5OD021356-03)

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Etoposide
Glioblastoma
Brain Neoplasms
Glioma
Therapeutics