Translating Scientific Evidence into Practice using Digital Medicine and Electronic Patient Reported Outcomes

Project: Research project

Project Details


The goal of this CTSA Consortium proposal “Translating Scientific Evidence into Practice using Digital Medicine and Electronic Patient Reported Outcomes” is to build an evidence-based approach for Digital Medicine to bridge the current T3 (incorporate into practice the optimal intervention) and T4 (to provide communities with the optimal intervention) translational gaps in care delivery of inflammatory bowel disease (IBD) patients. Specially, we plan to create a ‘learning health system laboratory’ with three CTSA hubs in different geographical regions collaborating with patient partners and a national provider society, to implement and evaluate a Digital transformation network (DTN) for IBD patients and share the implementation science to make it replicable. IBD impacts over 1.8 million patients and families with unpredictable IBD symptoms (including diarrhea, weight loss, and rectal bleeding) and increased risk for colorectal cancer and surgeries, these factors can have a profound social, professional, and emotional impact on those with the disease, as well as those who care for them. To control symptoms and avoid hospitalizations and surgery, proactive care through “Treat to Target” strategy (normalization of patient’s symptoms and inflammatory markers) is recommended but not widely adopted due to lack of infrastructure and translational science to support scalable remote monitoring.
Effective start/end date4/20/206/30/23


  • Icahn School of Medicine at Mount Sinai (0255-D514-4609 // 5U01TR002997-04)
  • National Center for Advancing Translational Sciences (0255-D514-4609 // 5U01TR002997-04)


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