Project Details
Description
Traumatic brain injury afflicts approximately three million Americans every year with a high rate of long-term cognitive and psychiatric morbidity. Chronic neuroinflammation resulting from the constitutive activation of microglia is complicit in this process and represents a complex interplay between the injured brain, microglia, and the gut microbiome via the gut-brain axis. However, the mechanism(s) underlying gut microbiota-microglia interaction have yet to be elucidated.
Status | Active |
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Effective start/end date | 8/1/22 → 7/31/27 |
Funding
- National Institute of Neurological Disorders and Stroke (5R01NS127865-03)
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