Food allergy is a serious and growing health problem, reported by our group in 2013 to affect 8% of children in the United States (US).The extent to which food allergy affects adults in the US is not well established and prevalence estimates range from 1% to 9.1%.Among food allergic adults, children, and their caregivers, food allergy is associated with lower quality of life (QOL), intense fear and anxiety, and higher economic costs. In addition, negative health outcomes are often compounded by limited treatment options. Due to the ubiquity of allergenic foods in the social environment, accidental ingestions and allergic reactions are common, resulting in increasing ED visits for anaphylaxis, impaired FAQoL and deaths. Specific Aims and Methods: The goal of this study is to analyze and disseminate survey data collected from concurrent nationally representative samples of 40,000 children and 40,000 adults in order to: 1) Determine the overall prevalence, severity and geographic distribution of food allergy in the US among children and adults (including adult-onset FA) by assessing overall population-weighted FA prevalence and allergy to each of the 10 most common food allergens, 2) Characterize FA management practices and outcomes of adults and children with FA, 3) Determine socio-demographic, behavioral, and environmental factors, and 4) Develop predictive models to estimate the future population-level FA burden in the US. Significance: This study will help determine prevalence, severity, and distribution, of food allergy among adults and also update these data for the first time since 2010 for US children. These findings will also improve understanding of the interplay of socio-environmental and individual factors on the development of new-onset food allergy and the development of tolerance among adults and children. By developing unique models of future population-level food allergy burden in the US based on current population-level estimates, we will inform the context of future food allergy research regarding diagnosis, management, and treatment of this rapidly emerging, multi-generational health concern.
|Effective start/end date||12/15/17 → 11/30/19|
- Ann & Robert H. Lurie Children's Hospital of Chicago (901526-NU//R21AI135702-02)
- National Institute of Allergy and Infectious Diseases (901526-NU//R21AI135702-02)
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