USC/UCLA Center on Biodemography and Population Health

This project involves analysis of three publicly available datasets to answer questions about how, when, and why poverty affects regulation of the immune system, as reflected in gene expression patterns of white blood cells. The Northwestern team consists of Greg Miller (PI), and two members of his laboratory group, Jennifer Kish, MPH and Alexa Freedman, PhD. Our team will: 1. Gather, clean, and integrate the datasets involved 2. Perform factor analyses to delineate clusters of co-expressed genes 3. Use linear models to relate these clusters to poverty and health 4. Prepare scientific manuscripts to describe the findings