Use of Adductomics for Identifying Early Detection Biomarkers for Ovarian Cancer

Project: Research project

Project Details

Description

Ovarian cancer is the fifth most prevalent cancer among women and is the
leading cause of gynecological cancer fatalities in the US. Because there are often no
signs of ovarian cancer until the disease has progressed to an advanced stage, identifying
sensitive and specific early detection biomarkers is of paramount importance. To address
this need, this proposal will apply a new cutting-edge approach called “adductomics” to
investigate candidate biomarkers for early ovarian cancer detection. While protein
adducts (addition products) have been used for decades as exposure biomarkers, they
have been neglected in discovery-based experiments as early diagnostic biomarkers for
cancer.
StatusFinished
Effective start/end date1/1/1412/31/15

Funding

  • Northwestern Memorial Hospital (Exhibit B.9)

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