Ms. Liu will perform isolation of human and murine bone marrow cells for analysis of RNA and protein. She will assist in bone marrow transplant studies in a murine leukemia model using transduced murine bone marrow cells. She will perform pre-clincial studies in this animal model to test various standard and novel approaches to leukemia therapeutics. These studies also involve mechanistic investigation of proteins and signaling pathways using transduced murine bone marrow cells and basic biochemical analysis, including protein purification, immunoprecipitation of DNA and protein, and protein activity analysis using ELISA techniques.
|Effective start/end date||7/1/19 → 9/30/22|
- Jesse Brown VA Medical Center (Agmt 09/01/20)
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.