Wake Forest REHAB-HFpEF

Project: Research project

Project Details


In HFpEF: comorbidity burden, frailty rates, physical dysfunction, quality of life, and depression were all significantly worse at baseline than among participants with the HFrEF phenotype. These data suggest that the intervention provides uniformly robust improvements in physical function and quality of life, and may reduce both mortality and rehospitalizations for patients with HFpEF , but is less promising for HFrEF. Primary Objective: – To determine whether an innovative, transitional, tailored, progressive, multi domain physical rehabilitation intervention will improve the combined endpoint of rehospitalizations or death and secondary outcome of major mobility disorder for hospitalized acute decompensated heart failure patients with HFpEF.
Effective start/end date11/15/227/31/27


  • Wake Forest University Health Sciences (1481-32041-11000001166 Amendment 1 // 5R01AG078153-02)
  • National Institute on Aging (1481-32041-11000001166 Amendment 1 // 5R01AG078153-02)


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