Wireless, bioresorbable neural stimulators for discovery in neuroscience

The proposed work will yield, wireless, battery-free and fully implantable electronics, coupled to bioresorbable stimulators, for targeted neuronal interfaces. In addition to the physical advantage of thin, flexible wireless control platforms, the injectable, filamentary bioresorbable electrodes will provide high performance operation with a slow, controlled dissolution into biocompatible end products after a period of functional operation. The specific designs outlined here involve highly doped silicon nanomembranes (Si NMs) as the electrodes. The wireless systems enable interference-free behavioral experiments on freely moving animal models, without tethered restraints. Collectively, a successful effort will yield a set of tools and therapeutic systems with major advantages over currently available options.