TY - JOUR
T1 - α-l-Fucosidase m cystic fibrosis
T2 - analysis of skin fibroblasts and liver
AU - Harris, Ann
AU - Swallow, Dallas
N1 - Funding Information:
Ann Harris is the recipient of a Research Training Fellowship from Action Research for the Crippled Child. The work was in part supported by the Department of Health and Social Security.
PY - 1981/10/26
Y1 - 1981/10/26
N2 - The lysosomal enzyme α-l-fucosidase has been examined by thin layer gel and column isoelectric focusing in skin fibroblasts and liver from patients with cystic fibrosis and controls. All three common phenotypes of the enzyme were observed in both control and CF fibroblasts. When individuals of the same α-l-fucosidase phenotype were compared, no major differences between the isozyme profiles of cystic fibrosis patients and controls were detected in either fibroblasts or liver tissue.
AB - The lysosomal enzyme α-l-fucosidase has been examined by thin layer gel and column isoelectric focusing in skin fibroblasts and liver from patients with cystic fibrosis and controls. All three common phenotypes of the enzyme were observed in both control and CF fibroblasts. When individuals of the same α-l-fucosidase phenotype were compared, no major differences between the isozyme profiles of cystic fibrosis patients and controls were detected in either fibroblasts or liver tissue.
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U2 - 10.1016/0009-8981(81)90020-6
DO - 10.1016/0009-8981(81)90020-6
M3 - Article
C2 - 7296885
AN - SCOPUS:0019416139
VL - 116
SP - 171
EP - 178
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
SN - 0009-8981
IS - 2
ER -