π-Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation

Anzhela Galstyan*, Yogesh Kumar Maurya, Halina Zhylitskaya, Youn Jue Bae, Yi Lin Wu, Michael R. Wasielewski, Tadeusz Lis, Ulrich Dobrindt, Marcin Stępień

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Free base, zinc and palladium π-extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram-positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex.

Original languageEnglish (US)
Pages (from-to)8262-8266
Number of pages5
JournalChemistry - A European Journal
Volume26
Issue number37
DOIs
StatePublished - Jul 2 2020

Keywords

  • antimicrobial
  • photosensitizers
  • singlet oxygen
  • triplet state
  • π-extended porphyrins

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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