18F-NaF and 18F-FDG PET/CT in Gorham-Stout Disease

Georgios Z. Papadakis, Corina Millo, Ulas Bagci, Jenny Blau, Michael T. Collins

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Gorham-Stout disease (GSD) is an extremely rare skeletal disorder of unknown etiology characterized by benign proliferation of vascular or lymphatic channels, leading to progressive bone resorption. We report on a patient diagnosed with GSD affecting the right scapula and the right ribs, who underwent PET/CT scans using F-FDG and F-NaF. The remnant upper portion of the affected scapula did not show F-FDG uptake but demonstrated markedly increased F-NaF activity. Furthermore, intense F-NaF activity was seen on the right posterior ribs, which were actively being resorbed, suggesting the potential application of F-NaF-PET/CT imaging in GSD diagnosis and follow-up.

Original languageEnglish (US)
Pages (from-to)884-885
Number of pages2
JournalClinical nuclear medicine
Volume41
Issue number11
StatePublished - Nov 1 2016

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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