18F sodium fluoride PET/CT detects osseous metastases from breast cancer missed on FDG PET/CT with marrow rebound.

Ryan Avery*, Phillip H. Kuo

*Corresponding author for this work

Research output: Contribution to journalArticle

7 Scopus citations


Intense FDG uptake by bone marrow following recent chemotherapy limits evaluation for osseous metastases. The impact of marrow rebound on accuracy of (18)F-fluoride PET/CT is unclear. A 73-year-old woman with breast cancer presented for restaging FDG PET/CT, which showed intense activity throughout almost the entire axial skeleton and no osseous metastases. An (18)F-fluoride PET/CT performed 7 days later identified multiple osseous metastases in the spine, ribs, and pelvis. This case demonstrates that (18)F-fluoride PET/CT should be considered for the evaluation of osseous metastases in patients with rebound marrow uptake on FDG PET/CT.

Original languageEnglish (US)
Pages (from-to)746-748
Number of pages3
JournalClinical nuclear medicine
Issue number9
StatePublished - Sep 2013


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this