2,3-Dihydroxy-N-methylbenzamide monohydrate

Jose Escalada, Danna Freedman, Eric J. Werner*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The synthesis of 2,3-dihyroxy-N-methylbenzamide (CAM-Me) monohydrate compound, was studied. CAM-Me was crystallized from deuterated acetone and water forming colourless blocks. Hydrogen bonding connects CAM-Me and water to give repeating pairs of planes. These planes are linked together into pairs by the hydrogen-bond donation of O4 to the hydroxyl O11. The orientation of the hydrogen bonds in CAM-Me differs from that of gas phase calculations and hydrogen-bonding schemes in similar molecules for which there is no coordinating solvent present. It is observed that the meta-hydroxyl group donates a hydrogen bond and there is no clear trend that predicts whether this hydrogen bond will be inter- or intramolecular in similar structures.

Original languageEnglish (US)
JournalActa Crystallographica Section E: Structure Reports Online
Volume60
Issue number8
DOIs
StatePublished - Aug 1 2004

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics

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