The synthesis of 2,3-dihyroxy-N-methylbenzamide (CAM-Me) monohydrate compound, was studied. CAM-Me was crystallized from deuterated acetone and water forming colourless blocks. Hydrogen bonding connects CAM-Me and water to give repeating pairs of planes. These planes are linked together into pairs by the hydrogen-bond donation of O4 to the hydroxyl O11. The orientation of the hydrogen bonds in CAM-Me differs from that of gas phase calculations and hydrogen-bonding schemes in similar molecules for which there is no coordinating solvent present. It is observed that the meta-hydroxyl group donates a hydrogen bond and there is no clear trend that predicts whether this hydrogen bond will be inter- or intramolecular in similar structures.
|Original language||English (US)|
|Journal||Acta Crystallographica Section E: Structure Reports Online|
|State||Published - Aug 1 2004|
ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics