@inproceedings{efb35df67156490bac83964ff8cdeb60,
title = "2D/3D cryo X-ray fluorescence imaging at the bionanoprobe at the advanced photon source",
abstract = "Trace elements, particularly metals, play very important roles in biological systems. Synchrotron-based hard X-ray fluorescence microscopy offers the most suitable capabilities to quantitatively study trace metals in thick biological samples, such as whole cells and tissues. In this manuscript, we have demonstrated X-ray fluorescence imaging of frozen-hydrated whole cells using the recent developed Bionanoprobe (BNP). The BNP provides spatial resolution down to 30 nm and cryogenic capabilities. Frozen-hydrated biological cells have been directly examined on a sub-cellular level at liquid nitrogen temperatures with minimal sample preparation.",
author = "S. Chen and T. Paunesku and Y. Yuan and J. Deng and Q. Jin and Hong, {Y. P.} and Vine, {D. J.} and B. Lai and C. Flachenecker and B. Hornberger and K. Brister and C. Jacobsen and Woloschak, {G. E.} and S. Vogt",
note = "Publisher Copyright: {\textcopyright} 2016 AIP Publishing LLC.; 12th International Conference on X-Ray Microscopy, XRM 2014 ; Conference date: 26-10-2014 Through 31-10-2014",
year = "2016",
month = jan,
day = "28",
doi = "10.1063/1.4937522",
language = "English (US)",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "{de Jonge}, {Martin D.} and Paterson, {David J.} and Ryan, {Christopher G.}",
booktitle = "XRM 2014",
}