3-D bioprinting technologies in tissue engineering and regenerative medicine: Current and future trends

Elliot S. Bishop, Sami Mostafa, Mikhail Pakvasa, Hue H. Luu, Michael J. Lee, Jennifer Moriatis Wolf, Guillermo A. Ameer, Tong Chuan He, Russell R. Reid*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

187 Scopus citations

Abstract

Advances in three-dimensional (3D) printing have increased feasibility towards the synthesis of living tissues. Known as 3D bioprinting, this technology involves the precise layering of cells, biologic scaffolds, and growth factors with the goal of creating bioidentical tissue for a variety of uses. Early successes have demonstrated distinct advantages over conventional tissue engineering strategies. Not surprisingly, there are current challenges to address before 3D bioprinting becomes clinically relevant. Here we provide an overview of 3D bioprinting technology and discuss key advances, clinical applications, and current limitations. While 3D bioprinting is a relatively novel tissue engineering strategy, it holds great potential to play a key role in personalized medicine.

Original languageEnglish (US)
Pages (from-to)185-195
Number of pages11
JournalGenes and Diseases
Volume4
Issue number4
DOIs
StatePublished - Dec 2017

Keywords

  • 3D printing
  • Additive manufacturing
  • Bioprinting
  • CAD/CAM
  • Tissue engineering

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Genetics(clinical)
  • Cell Biology

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