TY - GEN
T1 - 3D analysis of transmural myocardial strain from sonomicrometric crystals in the open chest dog
AU - Saracino, G.
AU - Ragnoni, A.
AU - Popovic, Z.
AU - Corsi, C.
AU - Greenberg, N.
AU - Lamberti, C.
AU - Thomas, J. D.
PY - 2008
Y1 - 2008
N2 - Interest in left ventricular (LV) mechanics has recently focused on detailed 3D analysis of LV deformations. Our goal is to investigate transmural strain variability within the normal ventricle and during the early stages of ischemia using sonomicrometric crystals implanted into canine LV wall. In this study 3 open chest dog models were implanted in a two-tetrahedron configuration with three crystals on the epicardial surface, three on the endocardial surface and one in the LV midwall. Our algorithm numerically reconstructs local ventricular 3D geometry and mechanics including radial, longitudinal and circumferential strain. Along with EKG, pressure-volume signals were acquired using a catheter introduced to LV from the femoral artery. Results obtained clearly illustrate a difference in strain across the myocardium. This study shows that the method can disclose important information regarding transmural variability in animal model and further investigation with different pacing and conditions could enhance understating of LV Mechanics.
AB - Interest in left ventricular (LV) mechanics has recently focused on detailed 3D analysis of LV deformations. Our goal is to investigate transmural strain variability within the normal ventricle and during the early stages of ischemia using sonomicrometric crystals implanted into canine LV wall. In this study 3 open chest dog models were implanted in a two-tetrahedron configuration with three crystals on the epicardial surface, three on the endocardial surface and one in the LV midwall. Our algorithm numerically reconstructs local ventricular 3D geometry and mechanics including radial, longitudinal and circumferential strain. Along with EKG, pressure-volume signals were acquired using a catheter introduced to LV from the femoral artery. Results obtained clearly illustrate a difference in strain across the myocardium. This study shows that the method can disclose important information regarding transmural variability in animal model and further investigation with different pacing and conditions could enhance understating of LV Mechanics.
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U2 - 10.1109/CIC.2008.4749237
DO - 10.1109/CIC.2008.4749237
M3 - Conference contribution
AN - SCOPUS:62249169292
SN - 1424437067
SN - 9781424437061
T3 - Computers in Cardiology
SP - 1097
EP - 1100
BT - Computers in Cardiology 2008, CAR
T2 - Computers in Cardiology 2008, CAR
Y2 - 14 September 2008 through 17 September 2008
ER -