3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs

David B. Kolesky; Ryan L. Truby; A. Sydney Gladman; Travis A. Busbee; Kimberly A. Homan; Jennifer A. Lewis

doi:10.1002/adma.201305506

3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs

David B. Kolesky, Ryan L. Truby, A. Sydney Gladman, Travis A. Busbee, Kimberly A. Homan, Jennifer A. Lewis^*

^*Corresponding author for this work

Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

1678 Scopus citations

Abstract

A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.

Original language	English (US)
Pages (from-to)	3124-3130
Number of pages	7
Journal	Advanced Materials
Volume	26
Issue number	19
DOIs	https://doi.org/10.1002/adma.201305506
State	Published - May 21 2014

Funding

Keywords

3D printing
biomaterials
bioprinting
tissue engineering
vasculature

ASJC Scopus subject areas

Mechanics of Materials
Mechanical Engineering
General Materials Science

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title = "3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs",

abstract = "A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.",

keywords = "3D printing, biomaterials, bioprinting, tissue engineering, vasculature",

author = "Kolesky, {David B.} and Truby, {Ryan L.} and Gladman, {A. Sydney} and Busbee, {Travis A.} and Homan, {Kimberly A.} and Lewis, {Jennifer A.}",

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AU - Truby, Ryan L.

AU - Gladman, A. Sydney

AU - Busbee, Travis A.

AU - Homan, Kimberly A.

AU - Lewis, Jennifer A.

PY - 2014/5/21

Y1 - 2014/5/21

N2 - A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.

AB - A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.

KW - 3D printing

KW - biomaterials

KW - bioprinting

KW - tissue engineering

KW - vasculature

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ER -

3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs

Abstract

Funding

Keywords

ASJC Scopus subject areas

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