4. Gastrointestinal mucosal immunity

Barry K. Wershil; Glenn T. Furuta

doi:10.1016/j.jaci.2007.10.023

4. Gastrointestinal mucosal immunity

Barry K. Wershil, Glenn T. Furuta^*

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

Abstract

Mucosal surfaces constitute a large host-environmental interface that must be protected from pathogenic organisms. The mucosal immune system has evolved as a distinct immune organ functioning independently from its systemic counterpart. The mucosal immune system has the difficult task of mounting protective responses to invading microorganisms while maintaining a state of nonresponsiveness to commensal bacteria and food antigens. The system has unique cellular components and functional aspects that permit it to carry out this dual role.

Original language	English (US)
Pages (from-to)	S380-S383
Journal	Journal of Allergy and Clinical Immunology
Volume	121
Issue number	2 SUPPL. 2
DOIs	https://doi.org/10.1016/j.jaci.2007.10.023
State	Published - Feb 2008

Keywords

Mucosal immunity
oral tolerance

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Access to Document

10.1016/j.jaci.2007.10.023

Cite this

@article{e4c34a93364e43ebadbc3450511dc065,

title = "4. Gastrointestinal mucosal immunity",

abstract = "Mucosal surfaces constitute a large host-environmental interface that must be protected from pathogenic organisms. The mucosal immune system has evolved as a distinct immune organ functioning independently from its systemic counterpart. The mucosal immune system has the difficult task of mounting protective responses to invading microorganisms while maintaining a state of nonresponsiveness to commensal bacteria and food antigens. The system has unique cellular components and functional aspects that permit it to carry out this dual role.",

keywords = "Mucosal immunity, oral tolerance",

author = "Wershil, {Barry K.} and Furuta, {Glenn T.}",

year = "2008",

month = feb,

doi = "10.1016/j.jaci.2007.10.023",

language = "English (US)",

volume = "121",

pages = "S380--S383",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Mosby Inc.",

number = "2 SUPPL. 2",

}

TY - JOUR

T1 - 4. Gastrointestinal mucosal immunity

AU - Wershil, Barry K.

AU - Furuta, Glenn T.

PY - 2008/2

Y1 - 2008/2

N2 - Mucosal surfaces constitute a large host-environmental interface that must be protected from pathogenic organisms. The mucosal immune system has evolved as a distinct immune organ functioning independently from its systemic counterpart. The mucosal immune system has the difficult task of mounting protective responses to invading microorganisms while maintaining a state of nonresponsiveness to commensal bacteria and food antigens. The system has unique cellular components and functional aspects that permit it to carry out this dual role.

AB - Mucosal surfaces constitute a large host-environmental interface that must be protected from pathogenic organisms. The mucosal immune system has evolved as a distinct immune organ functioning independently from its systemic counterpart. The mucosal immune system has the difficult task of mounting protective responses to invading microorganisms while maintaining a state of nonresponsiveness to commensal bacteria and food antigens. The system has unique cellular components and functional aspects that permit it to carry out this dual role.

KW - Mucosal immunity

KW - oral tolerance

UR - http://www.scopus.com/inward/record.url?scp=38649137730&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38649137730&partnerID=8YFLogxK

U2 - 10.1016/j.jaci.2007.10.023

DO - 10.1016/j.jaci.2007.10.023

M3 - Article

C2 - 18241686

AN - SCOPUS:38649137730

VL - 121

SP - S380-S383

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

SN - 0091-6749

IS - 2 SUPPL. 2

ER -

4. Gastrointestinal mucosal immunity

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this