4. Gastrointestinal mucosal immunity

Barry K. Wershil, Glenn T. Furuta*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

Mucosal surfaces constitute a large host-environmental interface that must be protected from pathogenic organisms. The mucosal immune system has evolved as a distinct immune organ functioning independently from its systemic counterpart. The mucosal immune system has the difficult task of mounting protective responses to invading microorganisms while maintaining a state of nonresponsiveness to commensal bacteria and food antigens. The system has unique cellular components and functional aspects that permit it to carry out this dual role.

Original languageEnglish (US)
Pages (from-to)S380-S383
JournalJournal of Allergy and Clinical Immunology
Volume121
Issue number2 SUPPL. 2
DOIs
StatePublished - Feb 2008

Keywords

  • Mucosal immunity
  • oral tolerance

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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