4D radial coronary artery imaging within a single breath-hold: Cine angiography with phase-sensitive fat suppression (CAPS)

Jaeseok Park, Andrew C. Larson, Qiang Zhang, Orlando Simonetti, Debiao Li*

*Corresponding author for this work

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Coronary artery data acquisition with steady-state free precession (SSFP) is typically performed in a single frame in mid-diastole with a spectrally selective pulse to suppress epicardial fat signal. Data are acquired while the signal approaches steady state, which may lead to artifacts from the SSFP transient response. To avoid sensitivity to cardiac motion, an accurate trigger delay and data acquisition window must be determined. Cine data acquisition is an alternative approach for resolving these limitations. However, it is challenging to use conventional fat saturation with cine imaging because it interrupts the steady-state condition. The purpose of this study was to develop a 4D coronary artery imaging technique, termed "cine angiography with phase-sensitive fat suppression" (CAPS), that would result in high temporal and spatial resolution simultaneously. A 3D radial stacked k-space was acquired over the entire cardiac cycle and then interleaved with a sliding window. Sensitivity-encoded (SENSE) reconstruction with rescaling was developed to reduce streak artifact and noise. Phase-sensitive SSFP was employed for fat suppression using phase detection. Experimental studies were performed on volunteers. The proposed technique provides high-resolution coronary artery imaging for all cardiac phases, and allows multiple images at mid-diastole to be averaged, thus enhancing the signal-to-noise ratio (SNR) and vessel delineation.

Original languageEnglish (US)
Pages (from-to)833-840
Number of pages8
JournalMagnetic resonance in medicine
Volume54
Issue number4
DOIs
StatePublished - Oct 1 2005

Keywords

  • Coronary MRA
  • Fat suppression
  • Magnetic resonance imaging (MRI)
  • Parallel MRI
  • Rapid imaging
  • SSFP

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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