7 - Nondiffuse Astrocytoma Variants

Daniel J. Brat; Arie Perry

doi:10.1016/B978-0-323-44941-0.00007-2

7 - Nondiffuse Astrocytoma Variants

Daniel J. Brat^*, Arie Perry

^*Corresponding author for this work

Pathology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

The designation of "astrocytoma" includes a small subset of tumors with astrocytic differentiation that are lower grade and better circumscribed than the diffuse astrocytomas. These tumors arise in the pediatric population most frequently, but are also occasionally noted in adults and include the pilocytic astrocytoma, pleomorphic xanthoastrocytoma (PXA), and subependymal giant cell astrocytoma (SEGA). Each of these has distinct localizations, histologic appearances, molecular genetic profiles, and natural histories, which is generally more favorable than the diffuse astrocytomas.

Original language	English (US)
Title of host publication	Practical Surgical Neuropathology
Subtitle of host publication	A Diagnostic Approach A Volume in the Pattern Recognition Series
Publisher	Elsevier Inc
Pages	125-143
Number of pages	19
ISBN (Print)	9780323449410
DOIs	https://doi.org/10.1016/B978-0-323-44941-0.00007-2
State	Published - Jan 1 2018

Keywords

Pilocytic astrocytoma
Pleomorphic xanthoastrocytoma
Subependymal giant cell astrocytoma

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-323-44941-0.00007-2

Cite this

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AU - Perry, Arie

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N2 - The designation of "astrocytoma" includes a small subset of tumors with astrocytic differentiation that are lower grade and better circumscribed than the diffuse astrocytomas. These tumors arise in the pediatric population most frequently, but are also occasionally noted in adults and include the pilocytic astrocytoma, pleomorphic xanthoastrocytoma (PXA), and subependymal giant cell astrocytoma (SEGA). Each of these has distinct localizations, histologic appearances, molecular genetic profiles, and natural histories, which is generally more favorable than the diffuse astrocytomas.

AB - The designation of "astrocytoma" includes a small subset of tumors with astrocytic differentiation that are lower grade and better circumscribed than the diffuse astrocytomas. These tumors arise in the pediatric population most frequently, but are also occasionally noted in adults and include the pilocytic astrocytoma, pleomorphic xanthoastrocytoma (PXA), and subependymal giant cell astrocytoma (SEGA). Each of these has distinct localizations, histologic appearances, molecular genetic profiles, and natural histories, which is generally more favorable than the diffuse astrocytomas.

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KW - Pleomorphic xanthoastrocytoma

KW - Subependymal giant cell astrocytoma

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BT - Practical Surgical Neuropathology

PB - Elsevier Inc

ER -

7 - Nondiffuse Astrocytoma Variants

Abstract

Keywords

ASJC Scopus subject areas

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