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• Review article

  Targeting AMPK in the treatment of malignancies

  Vakana, E., Altman, J. K. & Platanias, L. C., Feb 1 2012, In: Journal of Cellular Biochemistry. 113, 2, p. 404-409 6 p.

  Research output: Contribution to journal › Review article › peer-review
  34 Scopus citations

• Targeting angiogenesis in colorectal cancer tyrosine kinase inhibitors

  Kircher, S. M., Nimeiri, H. S. & Benson, A. B., Jan 1 2016, In: Cancer Journal (United States). 22, 3, p. 182-189 8 p.

  Research output: Contribution to journal › Review article › peer-review
  21 Scopus citations

• Targeting angiogenesis in ovarian cancer

  Schmitt, J. & Matei, D., Jun 2012, In: Cancer Treatment Reviews. 38, 4, p. 272-283 12 p.

  Research output: Contribution to journal › Review article › peer-review
  41 Scopus citations

• Targeting antioxidants for cancer therapy

  Glasauer, A. & Chandel, N. S., Nov 1 2014, In: Biochemical Pharmacology. 92, 1, p. 90-101 12 p.

  Research output: Contribution to journal › Review article › peer-review
  294 Scopus citations

• Targeting aurora kinases in cancer treatment

  Kelly, K. R., Ecsedy, J., Mahalingam, D., Nawrocki, S. T., Padmanabhan, S., Giles, F. J. & Carew, J. S., Dec 1 2011, In: Current Drug Targets. 12, 14, p. 2067-2078 12 p.

  Research output: Contribution to journal › Review article › peer-review
  38 Scopus citations

• Targeting autophagy: A novel anticancer strategy with therapeutic implications for imatinib resistance

  Carew, J. S., Nawrocki, S. T., Giles, F. J. & Cleveland, J. L., Dec 1 2008, In: Biologics: Targets and Therapy. 2, 2, p. 201-204 4 p.

  Research output: Contribution to journal › Review article › peer-review
  26 Scopus citations

• Targeting bet bromodomain proteins in solid tumors

  Sahai, V., Redig, A. J., Collier, K. A., Eckerdt, F. D. & Munshi, H. G., Aug 1 2016, In: Oncotarget. 7, 33, p. 53997-54009 13 p.

  Research output: Contribution to journal › Review article › peer-review
  69 Scopus citations

• Targeting Cancer Stemness in the Clinic: From Hype to Hope

  Saygin, C., Matei, D., Majeti, R., Reizes, O. & Lathia, J. D., Jan 3 2019, In: Cell stem cell. 24, 1, p. 25-40 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  220 Scopus citations

• Targeting cancer testis antigens in synovial sarcoma

  Mitchell, G., Pollack, S. M. & Wagner, M. J., Jun 3 2021, In: Journal for immunotherapy of cancer. 9, 6, e002072.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  2 Scopus citations

• Targeting cardiovascular inflammation: Next steps in clinical translation

  Lawler, P. R., Bhatt, D. L., Godoy, L. C., Lüscher, T. F., Bonow, R. O., Verma, S. & Ridker, P. M., Jan 1 2021, In: European heart journal. 42, 1, p. 113-131 19 p.

  Research output: Contribution to journal › Review article › peer-review
  59 Scopus citations

• Targeting CD73 to augment cancer immunotherapy

  Roh, M., Wainwright, D. A., Wu, J. D., Wan, Y. & Zhang, B., Aug 2020, In: Current Opinion in Pharmacology. 53, p. 66-76 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  30 Scopus citations

• Targeting costimulatory molecules to improve antitumor immunity

  Capece, D., Verzella, D., Fischietti, M., Zazzeroni, F. & Alesse, E., 2012, In: Journal of Biomedicine and Biotechnology. 2012, 926321.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  52 Scopus citations

• Targeting Epidermal Growth Factor Receptor in triple negative breast cancer: New discoveries and practical insights for drug development

  Costa, R., Shah, A. N., Santa-Maria, C. A., Cruz, M. R., Mahalingam, D., Carneiro, B. A., Chae, Y. K., Cristofanilli, M., Gradishar, W. J. & Giles, F. J., Feb 1 2017, In: Cancer Treatment Reviews. 53, p. 111-119 9 p.

  Research output: Contribution to journal › Review article › peer-review
  90 Scopus citations

• Targeting epidermal growth factor receptor variant III: A novel strategy for the therapy of malignant glioma

  Sonabend, A. M., Dana, K. & Lesniak, M. S., Dec 1 2007, In: Expert review of anticancer therapy. 7, 12 SUPPL.

  Research output: Contribution to journal › Review article › peer-review
  19 Scopus citations

• Targeting gastrointestinal stromal tumors: The role of regorafenib

  Schroeder, B., Li, Z., Cranmer, L. D., Jones, R. L. & Pollack, S. M., May 20 2016, In: OncoTargets and Therapy. 9, p. 3009-3016 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  10 Scopus citations

• Targeting GSK-3: A promising approach for cancer therapy?

  Ougolkov, A. V. & Billadeau, D. D., Feb 2006, In: Future Oncology. 2, 1, p. 91-100 10 p.

  Research output: Contribution to journal › Review article › peer-review
  107 Scopus citations

• Targeting HER2+ Breast Cancer Brain Metastases: A Review of Brain-Directed HER2-Directed Therapies

  Chiec, L. & Kumthekar, P., Feb 2022, In: CNS Drugs. 36, 2, p. 167-179 13 p.

  Research output: Contribution to journal › Review article › peer-review

• Targeting insulin-like growth factor-I and insulin-like growth factor-binding protein-3 signaling pathways: A novel therapeutic approach for asthma

  Lee, H., Kim, S. R., Oh, Y., Cho, S. H., Schleimer, R. P. & Lee, Y. C., Apr 2014, In: American journal of respiratory cell and molecular biology. 50, 4, p. 667-677 11 p.

  Research output: Contribution to journal › Review article › peer-review
  38 Scopus citations

• Targeting integrins in malignant glioma

  Tabatabai, G., Weller, M., Nabors, B., Picard, M., Reardon, D., Mikkelsen, T., Ruegg, C. & Stupp, R., Sep 2010, In: Targeted Oncology. 5, 3, p. 175-181 7 p.

  Research output: Contribution to journal › Review article › peer-review
  71 Scopus citations

• Targeting lethal minimal residual disease in small cell lung cancer

  Patel, J. D., Krug, L. M., Azzoli, C. G., Gomez, J., Kris, M. G. & Miller, V. A., Jan 1 2003, In: Seminars in Oncology. 30, 1, p. 79-85 7 p.

  Research output: Contribution to journal › Review article › peer-review
  5 Scopus citations

• Targeting maspin in endothelial cells to induce cell apoptosis

  Schaefer, J. S. & Zhang, M., Jun 1 2006, In: Expert Opinion on Therapeutic Targets. 10, 3, p. 401-408 8 p.

  Research output: Contribution to journal › Review article › peer-review
  9 Scopus citations

• Targeting MDM2 and MDMX in retinoblastoma

  Laurie, N. A., Schin-Shih, C. & Dyer, M. A., Nov 1 2007, In: Current Cancer Drug Targets. 7, 7, p. 689-695 7 p.

  Research output: Contribution to journal › Review article › peer-review
  38 Scopus citations

• Targeting metabolism for lupus therapy

  Mehta, M. M. & Chandel, N. S., Feb 11 2015, In: Science translational medicine. 7, 274

  Research output: Contribution to journal › Review article › peer-review
  11 Scopus citations

• Targeting mitochondria metabolism for cancer therapy

  Weinberg, S. E. & Chandel, N. S., Jan 1 2015, In: Nature Chemical Biology. 11, 1, p. 9-15 7 p.

  Research output: Contribution to journal › Review article › peer-review
  827 Scopus citations

• Targeting mitotic pathways for endocrine-related cancer therapeutics

  Agarwal, S. & Varma, D., Sep 1 2017, In: Endocrine-related cancer. 24, 9, p. T65-T82

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  4 Scopus citations

• Targeting mTOR signaling pathways and related negative feedback loops for the treatment of acute myeloid leukemia

  Carneiro, B. A., Kaplan, J. B., Altman, J. K., Giles, F. J. & Platanias, L. C., Jan 1 2015, In: Cancer Biology and Therapy. 16, 5, p. 648-656 9 p.

  Research output: Contribution to journal › Review article › peer-review
  26 Scopus citations

• Targeting myocardial substrate metabolism in heart failure: Potential for new therapies

  Ardehali, H., Sabbah, H. N., Burke, M. A., Sarma, S., Liu, P. P., Cleland, J. G. F., Maggioni, A., Fonarow, G. C., Abel, E. D., Campia, U. & Gheorghiade, M., Feb 2012, In: European Journal of Heart Failure. 14, 2, p. 120-129 10 p.

  Research output: Contribution to journal › Review article › peer-review
  117 Scopus citations

• Targeting nodal in malignant melanoma cells

  Postovit, L. M., Seftor, E. A., Seftor, R. E. B. & Hendrix, M. J. C., Apr 2007, In: Expert Opinion on Therapeutic Targets. 11, 4, p. 497-505 9 p.

  Research output: Contribution to journal › Review article › peer-review
  36 Scopus citations

• Targeting non-small cell lung cancer with epidermal growth factor tyrosine kinase inhibitors: Where do we stand, where do we go

  Patel, J. D., Pasche, B. & Argiris, A., Jun 1 2004, In: Critical Reviews in Oncology/Hematology. 50, 3, p. 175-186 12 p.

  Research output: Contribution to journal › Review article › peer-review
  8 Scopus citations

• Targeting novel signaling pathways for resistant acute myeloid leukemia

  Sakamoto, K. M., Grant, S., Saleiro, D., Crispino, J. D., Hijiya, N., Giles, F., Platanias, L. & Eklund, E. A., 2002, In: Reviews in Clinical and Experimental Hematology. 6, 1, p. x-xiii

  Research output: Contribution to journal › Review article › peer-review

• Targeting novel signaling pathways for resistant acute myeloid leukemia

  Sakamoto, K. M., Grant, S., Saleiro, D., Crispino, J. D., Hijiya, N., Giles, F., Platanias, L. & Eklund, E. A., Mar 1 2015, In: Molecular Genetics and Metabolism. 114, 3, p. 397-402 6 p.

  Research output: Contribution to journal › Review article › peer-review
  45 Scopus citations

• Targeting obstetric providers in interventions for obesity and gestational weight gain: A systematic review

  Kominiarek, M. A., O'Dwyer, L. C., Simon, M. A. & Plunkett, B. A., Oct 2018, In: PloS one. 13, 10, e0205268.

  Research output: Contribution to journal › Review article › peer-review
  10 Scopus citations

• Targeting of desmoglein 1 in exfoliative toxin-mediated disease

  Simpson, C. L., Green, K. J. & Getsios, S., Dec 2010, In: Expert Review of Dermatology. 5, 6, p. 659-670 12 p.

  Research output: Contribution to journal › Review article › peer-review

• Targeting of mRNAs by multiple miRNAs: The next step

  Peter, M. E., Apr 2010, In: Oncogene. 29, 15, p. 2161-2164 4 p.

  Research output: Contribution to journal › Review article › peer-review
  203 Scopus citations

• Targeting of p0071 to desmosomes and adherens junctions is mediated by different protein domains

  Hatzfeld, M., Green, K. J. & Sauter, H., Apr 1 2003, In: Journal of cell science. 116, 7, p. 1219-1233 15 p.

  Research output: Contribution to journal › Review article › peer-review
  59 Scopus citations

• Targeting of the VHL-Hypoxia-Inducible Factor-Hypoxia-Induced Gene Pathway for Renal Cell Carcinoma Therapy

  Sosman, J. A., Nov 2003, In: Journal of the American Society of Nephrology. 14, 11, p. 2695-2702 8 p.

  Research output: Contribution to journal › Review article › peer-review
  14 Scopus citations

• Targeting PARP in prostate cancer: Novelty, pitfalls, and promise

  Palmbos, P. L. & Hussain, M. H., May 15 2016, In: ONCOLOGY (United States). 30, 5

  Research output: Contribution to journal › Review article › peer-review
  6 Scopus citations

• Targeting PARP in Prostate Cancer: Novelty, Pitfalls, and Promise

  Palmbos, P. L. & Hussain, M. H., May 1 2016, In: Oncology (Williston Park, N.Y.). 30, 5, p. 377-385 9 p.

  Research output: Contribution to journal › Review article › peer-review
  6 Scopus citations

• Targeting Poison Exons to Treat Developmental and Epileptic Encephalopathy

  Aziz, M. C., Schneider, P. N. & Carvill, G. L., Sep 1 2021, In: Developmental Neuroscience. 43, 3, p. 241-246 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  5 Scopus citations

• Targeting protein kinases in central nervous system disorders

  Chico, L. K., Van Eldik, L. J. & Watterson, D. M., 2009, In: Nature Reviews Drug Discovery. 8, 11, p. 892-909 18 p.

  Research output: Contribution to journal › Review article › peer-review
  200 Scopus citations

• Targeting protein neddylation: A novel therapeutic strategy for the treatment of cancer

  Wang, M., Medeiros, B. C., Erba, H. P., Deangelo, D. J., Giles, F. J. & Swords, R. T., Mar 2011, In: Expert Opinion on Therapeutic Targets. 15, 3, p. 253-264 12 p.

  Research output: Contribution to journal › Review article › peer-review
  59 Scopus citations

• Targeting pulmonary vascular disease to improve global health - Pulmonary vascular disease: The global perspective

  Rich, S. & Herskowitz, A., Jun 1 2010, In: CHEST. 137, 6 SUPPL., p. 1S-5S

  Research output: Contribution to journal › Review article › peer-review
  10 Scopus citations

• Targeting sarcomas: Novel biological agents and future perspectives

  Mahalingam, D., Mita, A., Sankhala, K., Swords, R., Kelly, K., Giles, F. & Mita, M. M., Nov 26 2009, In: Current Drug Targets. 10, 10, p. 937-949 13 p.

  Research output: Contribution to journal › Review article › peer-review
  21 Scopus citations

• Targeting secondary injury in intracerebral haemorrhage-perihaematomal oedema

  Urday, S., Kimberly, W. T., Beslow, L. A., Vortmeyer, A. O., Selim, M. H., Rosand, J., Simard, J. M. & Sheth, K. N., Jan 1 2015, In: Nature Reviews Neurology. 11, 2, p. 111-122 12 p.

  Research output: Contribution to journal › Review article › peer-review
  145 Scopus citations

• Targeting small A β oligomers: The solution to an Alzheimer's disease conundrum?

  Klein, W. L., Krafft, G. A. & Finch, C. E., Apr 1 2001, In: Trends in Neurosciences. 24, 4, p. 219-224 6 p.

  Research output: Contribution to journal › Review article › peer-review
  901 Scopus citations

• Targeting the epidermal growth factor receptor in egfr-mutated lung cancer: Current and emerging therapies

  Khaddour, K., Jonna, S., Deneka, A., Patel, J. D., Abazeed, M. E., Golemis, E., Borghaei, H. & Boumber, Y., Jul 1 2021, In: Cancers. 13, 13, 3164.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  7 Scopus citations

• Targeting the FcεRI Pathway as a Potential Strategy to Prevent Food-Induced Anaphylaxis

  Dispenza, M. C., Bochner, B. S. & MacGlashan, D. W., Dec 17 2020, In: Frontiers in immunology. 11, 614402.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  5 Scopus citations

• Targeting the FMS-like tyrosine kinase 3 in acute myeloid leukemia

  Swords, R., Freeman, C. & Giles, F., Oct 2012, In: Leukemia. 26, 10, p. 2176-2185 10 p.

  Research output: Contribution to journal › Review article › peer-review
  102 Scopus citations

• "Targeting the Heart" in Heart Failure: Myocardial Recovery in Heart Failure With Reduced Ejection Fraction

  Wilcox, J. E., Fonarow, G. C., Ardehali, H., Bonow, R. O., Butler, J., Sauer, A. J., Epstein, S. E., Khan, S. S., Kim, R. J., Sabbah, H. N., Díez, J. & Gheorghiade, M., Sep 1 2015, In: JACC: Heart Failure. 3, 9, p. 661-669 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  39 Scopus citations

• Targeting the kinase activity of the BCR-ABL fusion protein in patients with chronic myeloid-leukemia

  Giles, F. J., Cortes, J. E. & Kantarjian, H. M., Nov 2005, In: Current Molecular Medicine. 5, 7, p. 615-623 9 p.

  Research output: Contribution to journal › Review article › peer-review
  31 Scopus citations