A Behavioral Cascade of HIV Seroadaptation Among US Men Who Have Sex with Men in the Era of PrEP and U = U

Steven M. Goodreau; Kevin M. Maloney; Travis H. Sanchez; Martina Morris; Patrick Janulis; Samuel M. Jenness

doi:10.1007/s10461-021-03266-0

A Behavioral Cascade of HIV Seroadaptation Among US Men Who Have Sex with Men in the Era of PrEP and U = U

Steven M. Goodreau^*, Kevin M. Maloney, Travis H. Sanchez, Martina Morris, Patrick Janulis, Samuel M. Jenness

^*Corresponding author for this work

Medical Social Sciences

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Seroadaptive behaviors help reduce HIV risk for some men who have sex with men (MSM), and have been well documented across MSM populations. Advancements in biomedical prevention have changed the contexts in which seroadaptive behaviors occur. We thus sought to estimate and compare the prevalence of four stages of the “seroadaptive cascade” by PrEP use in the recent era: knowledge of own serostatus, knowledge of partner serostatus; serosorting (matching by status), and condomless anal intercourse. Serosorting overall appeared to remain common, especially with casual and one-time partners. Although PrEP use did not impact status discussion, it did impact serosorting and the likelihood of having condomless anal intercourse. For respondents not diagnosed with HIV and not on PrEP, condomless anal intercourse occurred in just over half of relationships with HIV-positive partners who were not on treatment. Biomedical prevention has intertwined with rather than supplanted seroadaptive behaviors, while contexts involving neither persist.

Original language	English (US)
Pages (from-to)	3933-3943
Number of pages	11
Journal	AIDS and behavior
Volume	25
Issue number	12
DOIs	https://doi.org/10.1007/s10461-021-03266-0
State	Published - Dec 2021

Funding

This work was supported by National Institutes of Health Grant Nos. R21 MH112449 and R01 AI138783. Partial support for this research came from a Eunice Kennedy Shriver National Institute of Child Health and Human Development research infrastructure Grant, P2C HD042828, to the Center for Studies in Demography and Ecology at the University of Washington. The authors would like to thank the study participants, the full AMIS and ARTnet research teams, and the Network Modeling Group at the University of Washington. Special thanks to Ana Dobao and Marcos Llobera.

Keywords

Condom use
HIV-1
Men who have sex with men
Pre-exposure prophylaxis (PrEP)
Seroadaptive behaviors
Treatment as prevention (TasP)

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Infectious Diseases
Social Psychology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10461-021-03266-0

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abstract = "Seroadaptive behaviors help reduce HIV risk for some men who have sex with men (MSM), and have been well documented across MSM populations. Advancements in biomedical prevention have changed the contexts in which seroadaptive behaviors occur. We thus sought to estimate and compare the prevalence of four stages of the “seroadaptive cascade” by PrEP use in the recent era: knowledge of own serostatus, knowledge of partner serostatus; serosorting (matching by status), and condomless anal intercourse. Serosorting overall appeared to remain common, especially with casual and one-time partners. Although PrEP use did not impact status discussion, it did impact serosorting and the likelihood of having condomless anal intercourse. For respondents not diagnosed with HIV and not on PrEP, condomless anal intercourse occurred in just over half of relationships with HIV-positive partners who were not on treatment. Biomedical prevention has intertwined with rather than supplanted seroadaptive behaviors, while contexts involving neither persist.",

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A Behavioral Cascade of HIV Seroadaptation Among US Men Who Have Sex with Men in the Era of PrEP and U = U

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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