A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire

David Cella; Chanita Hughes; Amy Peterman; Chih Hung Chang; Beth N. Peshkin; Marc D. Schwartz; Lari Wenzel; Amy Lemke; Alfred C. Marcus; Caryn Lerman

doi:10.1037/0278-6133.21.6.564

A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire

David Cella^*, Chanita Hughes, Amy Peterman, Chih Hung Chang, Beth N. Peshkin, Marc D. Schwartz, Lari Wenzel, Amy Lemke, Alfred C. Marcus, Caryn Lerman

^*Corresponding author for this work

Medical Social Sciences

Research output: Contribution to journal › Article › peer-review

237 Scopus citations

Abstract

The Multidimensional Impact of Cancer Risk Assessment (MICRA) is a new tool to measure the specific impact of result disclosure after genetic testing. The authors compared its performance with that of questionnaires measuring general and cancer-specific distress. Participants (158 women) responded 1 month after they received genetic test results. The women were divided into 4 standard clinical test result groups: BRCA1/2 positive, BRCA1/2 negative, panel negative, and true negative. Factor analysis supported the formation of 3 subscales: Distress (6 items, α = .86), Uncertainty (9 items, α = .77), and Positive Experiences (4 items, α = .75). All 3 MICRA subscales differentiated participants who were BRCA 1/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants.

Original language	English (US)
Pages (from-to)	564-572
Number of pages	9
Journal	Health Psychology
Volume	21
Issue number	6
DOIs	https://doi.org/10.1037/0278-6133.21.6.564
State	Published - Nov 2002

Keywords

Cancer genetics
Cancer risk assessment
Genetic testing

ASJC Scopus subject areas

Psychiatry and Mental health
Applied Psychology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1037/0278-6133.21.6.564

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Cella, D., Hughes, C., Peterman, A., Chang, C. H., Peshkin, B. N., Schwartz, M. D., Wenzel, L., Lemke, A., Marcus, A. C., & Lerman, C. (2002). A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire. Health Psychology, 21(6), 564-572. https://doi.org/10.1037/0278-6133.21.6.564

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title = "A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire",

abstract = "The Multidimensional Impact of Cancer Risk Assessment (MICRA) is a new tool to measure the specific impact of result disclosure after genetic testing. The authors compared its performance with that of questionnaires measuring general and cancer-specific distress. Participants (158 women) responded 1 month after they received genetic test results. The women were divided into 4 standard clinical test result groups: BRCA1/2 positive, BRCA1/2 negative, panel negative, and true negative. Factor analysis supported the formation of 3 subscales: Distress (6 items, α = .86), Uncertainty (9 items, α = .77), and Positive Experiences (4 items, α = .75). All 3 MICRA subscales differentiated participants who were BRCA 1/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants.",

keywords = "Cancer genetics, Cancer risk assessment, Genetic testing",

author = "David Cella and Chanita Hughes and Amy Peterman and Chang, {Chih Hung} and Peshkin, {Beth N.} and Schwartz, {Marc D.} and Lari Wenzel and Amy Lemke and Marcus, {Alfred C.} and Caryn Lerman",

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doi = "10.1037/0278-6133.21.6.564",

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AU - Cella, David

AU - Hughes, Chanita

AU - Peterman, Amy

AU - Chang, Chih Hung

AU - Peshkin, Beth N.

AU - Schwartz, Marc D.

AU - Wenzel, Lari

AU - Lemke, Amy

AU - Marcus, Alfred C.

AU - Lerman, Caryn

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AB - The Multidimensional Impact of Cancer Risk Assessment (MICRA) is a new tool to measure the specific impact of result disclosure after genetic testing. The authors compared its performance with that of questionnaires measuring general and cancer-specific distress. Participants (158 women) responded 1 month after they received genetic test results. The women were divided into 4 standard clinical test result groups: BRCA1/2 positive, BRCA1/2 negative, panel negative, and true negative. Factor analysis supported the formation of 3 subscales: Distress (6 items, α = .86), Uncertainty (9 items, α = .77), and Positive Experiences (4 items, α = .75). All 3 MICRA subscales differentiated participants who were BRCA 1/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants.

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KW - Cancer risk assessment

KW - Genetic testing

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A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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