A case of acquired Brown syndrome treated with adalimumab

Kristi L. Michels; Sudhi P. Kurup; Megan L Curran; Risa Ann Alperin; Erika De Leon; Rebecca Mets-Halgrimson

doi:10.1016/j.jaapos.2020.01.003

A case of acquired Brown syndrome treated with adalimumab

Kristi L. Michels, Sudhi P. Kurup, Megan L Curran, Risa Ann Alperin, Erika De Leon, Rebecca Mets-Halgrimson^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

We present the case of a 4-year-old boy with acquired Brown syndrome of inflammatory origin. Without evidence of systemic inflammation, the disease typically resolves with oral steroids or nonsteroidal anti-inflammatory drugs. Refractory cases can be treated with local steroid injections or surgery. The present case of inflammatory Brown syndrome did not respond to conservative therapy, and parental concerns and wishes precluded more invasive treatments. Adalimumab was initiated and led to complete resolution of the disease.[Formula presented]

Original language	English (US)
Pages (from-to)	167-169
Number of pages	3
Journal	Journal of AAPOS
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/j.jaapos.2020.01.003
State	Published - Jun 2020

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Ophthalmology

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10.1016/j.jaapos.2020.01.003

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title = "A case of acquired Brown syndrome treated with adalimumab",

abstract = "We present the case of a 4-year-old boy with acquired Brown syndrome of inflammatory origin. Without evidence of systemic inflammation, the disease typically resolves with oral steroids or nonsteroidal anti-inflammatory drugs. Refractory cases can be treated with local steroid injections or surgery. The present case of inflammatory Brown syndrome did not respond to conservative therapy, and parental concerns and wishes precluded more invasive treatments. Adalimumab was initiated and led to complete resolution of the disease.[Formula presented]",

author = "Michels, {Kristi L.} and Kurup, {Sudhi P.} and Curran, {Megan L} and Alperin, {Risa Ann} and {De Leon}, Erika and Rebecca Mets-Halgrimson",

note = "Publisher Copyright: {\textcopyright} 2020 American Association for Pediatric Ophthalmology and Strabismus",

year = "2020",

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AU - Kurup, Sudhi P.

AU - Curran, Megan L

AU - Alperin, Risa Ann

AU - De Leon, Erika

AU - Mets-Halgrimson, Rebecca

PY - 2020/6

Y1 - 2020/6

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AB - We present the case of a 4-year-old boy with acquired Brown syndrome of inflammatory origin. Without evidence of systemic inflammation, the disease typically resolves with oral steroids or nonsteroidal anti-inflammatory drugs. Refractory cases can be treated with local steroid injections or surgery. The present case of inflammatory Brown syndrome did not respond to conservative therapy, and parental concerns and wishes precluded more invasive treatments. Adalimumab was initiated and led to complete resolution of the disease.[Formula presented]

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A case of acquired Brown syndrome treated with adalimumab

Abstract

ASJC Scopus subject areas

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