A case of acquired Brown syndrome treated with adalimumab

Kristi L. Michels, Sudhi P. Kurup, Megan L Curran, Risa Ann Alperin, Erika De Leon, Rebecca Mets-Halgrimson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We present the case of a 4-year-old boy with acquired Brown syndrome of inflammatory origin. Without evidence of systemic inflammation, the disease typically resolves with oral steroids or nonsteroidal anti-inflammatory drugs. Refractory cases can be treated with local steroid injections or surgery. The present case of inflammatory Brown syndrome did not respond to conservative therapy, and parental concerns and wishes precluded more invasive treatments. Adalimumab was initiated and led to complete resolution of the disease.[Formula presented]

Original languageEnglish (US)
Pages (from-to)167-169
Number of pages3
JournalJournal of AAPOS
Issue number3
StatePublished - Jun 2020

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology


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