A century of optocardiography

Bas J. Boukens, Igor R. Efimov

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

In the past decade, optical mapping provided crucial mechanistic insight into electromechanical function and the mechanism of ventricular fibrillation. Therefore, to date, optical mapping dominates experimental cardiac electrophysiology. The first cardiac measurements involving optics were done in the early 1900s using the fast cinematograph that later evolved into methods for high-resolution activation and repolarization mapping and stimulation of specific cardiac cell types. The field of 'optocardiography,' therefore, emerged as the use of light for recording or interfering with cardiac physiology. In this review, we discuss how optocardiography developed into the dominant research technique in experimental cardiology. Furthermore, we envision how optocardiographic methods can be used in clinical cardiology.

Original languageEnglish (US)
Article number6645408
Pages (from-to)115-125
Number of pages11
JournalIEEE Reviews in Biomedical Engineering
Volume7
DOIs
StatePublished - 2014

Keywords

  • Cardiology
  • conduction
  • electrophysiology
  • optical mapping
  • optogenetics

ASJC Scopus subject areas

  • Biomedical Engineering

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