@inbook{363991ed64e043d4a10556f31b6f10f8,
title = "A chemical approach to mapping nucleosomes at base pair resolution in yeast",
abstract = "Most eukaryotic DNA exists in DNA-protein complexes known as nucleosomes. The exact locations of nucleosomes along the genome play a critical role in chromosome functions and gene regulation. However, the current methods for nucleosome mapping do not provide the necessary accuracy to identify the precise nucleosome locations. Here we describe a new experimental approach that directly maps nucleosome center locations in vivo genome-wide at single base pair resolution.",
keywords = "Cleavage pattern, Cysteine, Hydroxyl radical, Nucleosome, Nucleosome center positioning score, S. cerevisiae, Template model",
author = "Brogaard, {Kristin R.} and Liqun Xi and Wang, {Ji Ping} and Jonathan Widom",
year = "2012",
doi = "10.1016/B978-0-12-391938-0.00014-8",
language = "English (US)",
series = "Methods in Enzymology",
publisher = "Academic Press Inc",
pages = "315--334",
booktitle = "Methods in Enzymology",
}